Figure 9.

Percentage distribution of SC/D-F9-induced apoptotic and necrotic breast and prostate cancer cells. MCF-7 and MDA-MB-231 cells were treated with DMSO (0.1%), SC/D-F9 (8.5 or 10.0 μg/ml, repectively), and tamoxifen (15 μM) for 24 hr while the PC-3 and DU-145 cells were treated with DMSO (0.1%), SC/D-F9 (7.4 and 7.2 μg/ml, respectively) and paclitaxel (50 nM) for 48 hr. The cells were stained with annexin V-FITC antibody and propidium iodide and analysed by flow cytometry.