Research article
In vitro antibacterial activity and acute toxicity studies of aqueous-methanol extract of Sida rhombifolia Linn. (Malvaceae)
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* Corresponding author: CA Pieme apieme@yahoo.fr
1 Department of Biochemistry, Faculty of Science PO Box 812 University of Yaoundé I Cameroon
2 Department of Biochemistry; Faculty of Science, University of Dschang; PO Box 67 Dschang-Cameroon
3 Department of Physiological Sciences and Biochemistry, Faculty of Medicine and Biomedical Sciences; PO Box 1364 University of Yaoundé, Yaoundé Cameroon
BMC Complementary and Alternative Medicine 2010, 10:40 doi:10.1186/1472-6882-10-40
Published: 27 July 2010Additional files
Additional file 1:
Table s1: Diameters of inhibition zone of different extracts of S. rhombifolia Linn. This table contents the diameters of inhibition zone of different extracts: MeOH,; water/MeOH (1v:4v); water/MeOH (1v:1v); water/MeOH (3v:2v); Gent: Gentamycin. All the extracts are tested at 500 μg/dic and 133 μg/disc for gentamicin.
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Additional file 2:
Table s2: Diameters of inhibition zone of different concentrations of aqueous methanol (1v:4v) of S. rhombifolia on bacteria. The table shows the diameters of inhibition zone of aqueous-methanol extract (1v:4v) of S. rhombifolia at the concentrations (50 μg/dic, 100 μg/dic, 150 μg/dic, 200 μg/dic)
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Additional file 3:
Table s3: Minimum inhibitory concentration of aqueous methanol extract (1v:4v) of S. rhombifolia on the parameter of inhibition of bacteria. This table shows the MICs of extract of S. rhombifolia against most sensitivebacteria (P. vulgaris, K. pneumonia, S. dysenteriae).
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Additional file 4:
Table s4: Body weights of rats after 8 days of acute toxicity of aqueous methanol extract of S. rhombifolia Linn. Variation of body weight of five groups of rats during acute toxicity assay.
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Additional file 5:
Table s5: Weights organs of rats in the acute toxicity of aqueous methanol extract of S. rhombifolia Linn. Variation of weight of organs (heart, lung, kidney and liver) 8 days after administration of unique dose of extract (acute toxicity)
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Additional file 6:
Table s6: Blood and liver homogenates biochemical index of rats after acute toxicity of aqueous-methanol extract of S. rhombifolia Linn. This table shows the results of biochemical parameters (ALAT, AST, ALP, Creatinine, protein) for serum and liver homogenates of five groups of rats after 8 days of administration of extract.
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