Table 5

Predominant pathogens isolated from blood of neutropenic and non-neutropenic patients treated with radiotherapy, chemotherapy and radio-chemotherapy (Group I, II. III)
Pathogens
    ANC (<500)
    ANC
(>500)
    ANC
(<500)
    ANC
(>500)
    ANC
(<500)
    ANC
(>500)
n = 64 n = 85 OR (95 % C.I) P n = 90 n = 55 OR (95 % C.I) P n = 112 n = 95 OR (95 % C.I) P
(A)Gram + ive 23(35.9) 18(21.1) 2.09(0.95-4.6) 0.07 52(5.7) 25(45.4 1.64(0.7-3.4) 0.20 61( 54.4) 35(36.8) 2.0(1.1-3.7) < 0.01**
S. aureus 15(23.4) 12(14.1) 0.94(0.21-4.1) 0.81 42(4.6) 11(2) 5.35 (1.6-17.6) < .001** 21( 18.7) 28(29.4) 0.1(0.0-0.3) < .001***
S. epidermidis 8(12.5) 6(7.0) 1.07(0.24-4.7) 0.81 10(1.1) 14(25.4) 0.19(0.0-0.6) < .001** 40(35.7) 7(7.3) 7.6(2.6-23.1) < .001***
(B)Gram -ive 26(40.6) 56(65.8) 0.35(0.1-0.7) < 0.001*** 24(2.6) 22(4) 0.55(0.2-1.1) 0.13 39(34.8) 42(44.2) 0.67(0.3-1.2) 0.21
E. coli 10(15.6) 9(10.5) 0.34(0.1-0.9) 0.04 7(7.7) 6(10.9) 1.10(0.2-4.7) 0.85 11(9.8) 17(17.8) 0.58(0.2-1.6) 0.35
P. aeruginosa 6(9.3) 28(32.9) 0.30(0.0-0.9) < 0.05* 7(7.7) 7(12.7) 0.88(0.2-3.7) 0.90 12(10.7) 12(12.6) 1.11(0.3-3.2) 0.97
K. pneumonia 5(7.8) 14(16.4) 0.71(0.1-2.5) 0.76 6(6.6) 5(9.0) 1.13(0.2-5.4) 0.86 10(8.9) 7(7.3) 1.72(0.5-5.8) 0.47
P. mirabilis 5(7.8) 5(5.8) 2.43(0.5-11.1) 0.27 4(4.4) 3(5.4) 1.27(0.2-8.4) 1.00 4(3.5) 5(5.2) 0.85(0.1-4.0) 1
P. vulgaris 0 0 0 0 0 1(1.8) 0.00(0.0-16.4) 0.47 2(1.7) 1(1.0) 1.84(0.1-53.7) 1
(C) Fungi 15(23.4) 11(12.9) 2.06(0.8-5.2) 0.14 14(15. 5) 8(14.5) 1.20(0.4-3.3) 0.88 12(10.7) 18(18.9) 0.51(0.2-1.2) 0.13
C. albicans 9(14.0) 6(7.0) 1.25(0.2-8.0) 1.00 8(8.8) 5(9.0) 0.80(0.0-6.5) 1.00 7(6.2) 10(10.5) 1.12(0.2-6.3) 0.82
A. fumigatus 6(9.3) 5(5.8) 0.80(0.1-5.0) 1.00 6(6.6) 3(5.4) 1.25(0.1-10.5) 1.00 5(4.4) 8(8.4) 0. 89(0.1-4.9) 0.82

Note: n = number of pathogens, % had been shown in parenthesis, ANC = absolute neutrophil count, ANC of <500 neutrophil/micro L (neutropenic), ANC > 500 neutrophil/micro L (non-neutropenic). P = Probability value of patients with an ANC of <500 neutrophil/micro L (neutropenic) vs. those with ANC >500 neutrophil/micro L (non-neutropenic). P < .05 * less significant, P < .01 ** significant, P < .001 *** highly significant.

Panghal et al.

Panghal et al. BMC Oral Health 2012 12:22   doi:10.1186/1472-6831-12-22

Open Data