Table 3

Predominant pathogens isolated from oral cavity of neutropenic and non-neutropenic patients treated with radiotherapy, chemotherapy and radiochemotherapy (Group I, II, III)
Pathogens
    ANC (<500)
    ANC
(>500)
    ANC
(<500)
    ANC
(>500)
    ANC
(<500)
    ANC
(>500)
n = 61 n = 82 OR (95 % C.I) P n = 79 n = 57 OR (95 % C.I) P n = 92 n = 83 OR (95 % C.I) P
(A)Gram + ive 13(21.3) 12(14.6) 1.58(0.61-4.0) 0.41 25(31.6) 18(31.5) 1.00(0.45-2.2) 0.85 39(42.3) 31(37.3) 1.23(0.6-2.3) 0.59
S. aureus 8(13.1) 6(7.3) 1.60(0.25-10.7) 0.85 18(22.7) 11(19.2) 1.64(0.38-7.2) 0.67 29(31.5) 15(18) 3.09(1.0-9.6) <0.05*
S. epidermidis 5(8.1) 6(7.3) 0.63(0.09-4.0) 0.85 7(8.8) 7(12.28) 0.61(0.14-2.2) 0.67 10(10.8) 16(19.2) 0.32(0.1-0.9) <0.05*
(B)Gram -ive 20(32.9) 18(21.9) 1.25(0.57-2.7) 0.68 43(54.4) 33(57.8) 0.87(0.41-1.8) 0.82 22(23.9) 29(34.9) 0.59(0.2-1.1) 0.15
E. coli 4(6.5) 6(7.3) 0.50(0.09-2.6) 0.46 7(8.8) 8(14.3) 0.61(0.17-2.1) 0.56 6(6.5) 8(9.6) 0.98(0.2-4.0) .77
P. aeruginosa 3(4.9) 4(4.8) 0.62(0.09-4.1) 0.68 5(6.3) 4(7) 0.95(0.20-4.7) 1.00 5(5.4) 7(8.4) 0.92(0.2-4.0) 0.82
K. pneumonia 5(8.1) 5(6.0) 0.87(0.16-4.5) 1 27(34.1) 13(22.8) 2.60(0.93-7.3) < 0.05* 4(4.3) 5(6) 1.07(0.2-5.5) 1
P. mirabilis 5(8.1) 3(3.6) 3(0.41-26.4) 0.40 4(5.0) 6(10.5) 0.46(0.10-2.1) 0.31 4(4.3) 5(6) 1.07(0.2-5.5) 1
P. vulgaris 3(3.8) 0 UN 0.23 0 2(3.5) 0.00(0.00-3.14)6 0.18 3(3.2) 4(4.8) 0.99(0.1-6.1) 1
(C) Fungi 28(45.9) 52(63.4) 0.49(0.24-1.0) < 0.05* 11(13.9) 6(10.5) 1.38(0.43-4.5) 0.74 31(33.6) 23(27.7) 1.33(0.6-2.6) 0.48
C. albicans 28(45.9) 40(48.7) 1.30 (1.12-1.5) < . 001*** 7(8.8) 6(10.5) 0.00(0.00-2.8) 0.23 26(28.2) 23(27.7) 0.00(0.0-1.5) <.05*
A. fumigatus 0 12 UN .02 4(5.0) 0 UN 1.0 5(5.4) 0 UN 1

Note: n = number of pathogens, UN: Undefined, % had been shown in parenthesis, ANC = absolute neutrophil count, ANC of <500 neutrophil/micro L (neutropenic), ANC >500 neutrophil/micro L (non-neutropenic). P = Probability value with an ANC of <500 neutrophil/micro L (neutropenic) vs. those with ANC >500 neutrophil/micro L (non-neutropenic). P < .05 * less significant, P < .01 ** significant, P < .001 *** highly significant.

Panghal et al.

Panghal et al. BMC Oral Health 2012 12:22   doi:10.1186/1472-6831-12-22

Open Data