Table 4

Comparison of our TSH reference intervals to previously published reference intervals (2.5, 50 and 97.5%) of different age groups.


Soldin et al., 1995 Abbott IMx®
 Zurakowski et al., 1999 DELFIA®
 Elmlinger et al., 2001 Immulite®
 Djemli et al., 2004 Access 2®
 Hübner et al., 2002 Advia Centaur®
 Kapelari et al., Advia Centaur®

Age





TSH
[mU/L]
 [mU/L]
 [mU/L]
 [mU/L]
 [mU/L]
 [mU/L]


n = 533
 n = 5,558
 n = 762
 n = 706
 n = 460
 n = 1,209

1 d – 7 d
 F: 0.72 – 13.1
 n.d.
 1.79 – 4.63 – 9.69
 F: 1.5 – 3.3 – 6.5
 0.13 – 9.23 a
 0.75 – 3.50 – 16.89

8 d–15 d
 M: 0.52 – 16.0
 n.d.
 1.80 – 3.71 – 7.97
 M: 0.7 – 2.4 – 9.8
 0.16 – 8.48 b

15 d – 1 m
n.d.
 n.d.



1 – 12 m
0.8 – 2.2 – 6.3
F: 1.0 – 2.4 – 5.7
 0.3 – 1.73 – 5.88 c
 1.30 – 2.85 – 7.09

1 – 2 y

0.63 – 2.04 – 4.12
 M: 0.7 – 2.1 – 5.9


2 – 3 y
 F: 0.46 – 8.1
 F: 0.7 – 2.0 – 5.9
n.d.
 0.42 – 1.98 – 4.79
 1.00 – 2.70 – 5.42

3 – 4 y
 M: 0.55 – 7.1
 M: 0.7 – 2.1 – 6.0
n.d.


4 – 5 y

0.53 – 1.60 – 2.94
 n.d.


5 – 6 y
 F: 0.36 – 5.8

n.d.


7 – 8
 M: 0.37 – 6.0
 F: 0.6 – 1.8 – 5.1
 0.80 – 1.86 – 3.48
 n.d.
 0.48 – 1.87 – 4.67
 0.90 – 2.30 – 4.40

9 – 10
M: 0.7 – 1.9 – 5.4
 0.85 – 2.00 – 3.50
 F: 0.9 – 2.0 – 4.0






M: 1.0 – 1.9 – 3.7


11

0.85 – 1.90 – 3.33



12
F: 0.5 – 1.5 – 4.4
 0.86 – 1.90 – 3.21
 F: 0.7 – 1.7 – 3.4
 0.53 – 1.78 – 4.58
 0.90 – 2.10 – 4.10

13
M: 0.6 – 1.7 – 4.9
 0.80 – 1.81 – 3.08
 M: 0.8 – 1.8 – 3.9


14

0.76 – 1.70 – 2.83



15

0.70 – 1.56 – 2.55



16

0.64 – 1.54 – 2.51
 F: 0.6 – 1.5 – 3.7
 0.56 – 2.00 – 4.53
 0.70 – 1.70 – 3.93

17
F: 0.5 – 1.3 – 3.9
 0.62 – 1.51 – 2.42
 M: 0.7 – 1.4 – 2.8


18 – 19
M: 0.5 – 1.6 – 4.4
 0.52 – 1.36 – 2.36
 n.d.

a 1 d – 3 d

b 4 d – 30 d

c 61 d – 12 m

Kapelari et al. BMC Endocrine Disorders 2008 8:15   doi:10.1186/1472-6823-8-15