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Parameters for structure parameter inference [21] |
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| Symbol |
Explanation |
Value |
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| αT |
Dilution factor for T4 (reciprocal of apparent volume of distribution) |
0,1 l-1 |
| βT |
Clearance exponent for T4 |
1,1 * 10-6 sec-1 |
| DT |
EC50 for TSH |
2,75 mU/l |
| K41 |
Dissociation constant T4-TBG |
2 * 1010 l/mol |
| K42 |
Dissociation constant T4-TBPA |
2 * 108 l/mol |
| α 31 |
Dilution factor for T3 |
0,026 l-1 |
| β 31 |
Clearance exponent for T3 |
8 * 10-6 sec-1 |
| KM1 |
Dissociation constant of type-1-deiodinase |
5 * 10-7 mol/l |
| K30 |
Dissociation constant T3-TBG |
2 * 109 l/mol |
Dietrich et al. BMC Endocrine Disorders 2008 8:13 doi:10.1186/1472-6823-8-13 |
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