Table 2

Cross-sectional and longitudinal associations of serum prolactin with metabolic syndrome and type 2 diabetes mellitus
Metabolic syndrome Type 2 diabetes mellitus
Cross-sectional Longitudinal Cross-sectional Longitudinal
Age-adjusted model Multivariable model Age-adjusted model Multivariable model Age-adjusted model Multivariable model Age-adjusted model Multivariable model
Prolactin Men
per SD increase 0.95 (0.89; 1.02) 0.95 (0.89; 1.01) 1.05 (0.95; 1.15) 1.04 (0.95; 1.14) 0.84 (0.73; 0.96)* 0.83 (0.72; 0.95)* 1.20 (0.98; 1.47) 1.19 (0.96; 1.47)
Quartiles (Q4 Ref.)
Q1 1.15 (0.97; 1.37) 1.15 (0.98; 1.35) 0.83 (0.64; 1.06) 0.87 (0.68; 1.10) 1.55 (1.12; 2.13)* 1.55 (1.13; 2.14)* 0.71 (0.41; 1.23) 0.78 (0.45; 1.35)
Q2 1.06 (0.89; 1.28) 1.03 (0.87; 1.22) 0.94 (0.74; 1.19) 0.94 (0.75; 1.18) 1.14 (0.81; 1.61) 1.11 (0.79; 1.56) 0.73 (0.42; 1.26) 0.78 (0.45; 1.33)
Q3 1.04 (0.87; 1.25) 1.02 (0.85; 1.21) 0.91 (0.72; 1.16) 0.94 (0.75; 1.18) 0.92 (0.63; 1.33) 0.92 (0.64; 1.33) 0.76 (0.44; 1.32) 0.72 (0.41; 1.27)
P for Trend 0.104 0.076 0.172 0.276 0.002 0.002 0.253 0.472
Women
per SD increase 0.92 (0.85; 1.00) 0.97 (0.90; 1.05) 0.89 (0.79; 1.00) 0.92 (0.83; 1.02) 0.81 (0.68; 0.95)* 0.84 (0.71; 0.98)* 1.09 (0.82; 1.45) 1.13 (0.89; 1.44)
Quartiles (Q4 Ref.)
Q1 1.32 (1.04; 1.66)* 1.11 (0.89; 1.39) 1.26 (0.95; 1.68) 1.15 (0.86; 1.53) 1.89 (1.21; 2.96)* 1.70 (1.10; 2.62)* 0.88 (0.44; 1.78) 0.73 (0.37; 1.43)
Q2 1.13 (0.89; 1.44) 1.04 (0.83; 1.32) 1.22 (0.91; 1.63) 1.16 (0.87; 1.54) 1.82 (1.15; 2.86)* 1.69 (1.09; 2.63)* 0.81 (0.39; 1.68) 0.75 (0.37; 1.50)
Q3 1.11 (0.86; 1.44) 1.07 (0.83; 1.32) 0.73 (0.51; 1.04) 0.78 (0.55; 1.11) 1.29 (0.77; 2.16) 1.26 (0.76; 2.09) 1.00 (0.48; 2.06) 1.08 (0.53; 2.20)
P for Trend 0.016 0.399 0.013 0.106 0.001 0.007 0.633 0.224

* p < 0.05; SD, standard deviation. The multivariable model was adjusted for age, body mass index, smoking status (three categories), physical activity, educational level (three categories), and alcohol consumption.

Balbach et al.

Balbach et al. BMC Endocrine Disorders 2013 13:12   doi:10.1186/1472-6823-13-12

Open Data