BMC Endocrine Disorders

tracked for impact factor

Open Access Research article

The transcription factor 7-like 2 (TCF7L2) polymorphism may be associated with focal arteriolar narrowing in Caucasians with hypertension or without diabetes: the ARIC Study

Yu Yan1, Ronald Klein2, Gerardo Heiss1, Cynthia J Girman1,3, Ethan M Lange10,4, Barbara E Klein2, Kathryn M Rose1, Eric Boerwinkle5, James S Pankow6, Frederick L Brancati7,8, Christie M Ballantyne9, Anna Köttgen7 and Kari E North1,10*

Author Affiliations

1 Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA

2 Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI, USA

3 Department of Epidemiology, Merck Research Laboratories, West Point, PA, USA

4 Department of Genetics, University of North Carolina, Chapel Hill, NC, USA

5 Human Genetics Center, University of Texas Health Science Center, Houston, TX, USA

6 Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA

7 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA

8 Department of Medicine, Johns Hopkins University, Baltimore, MD, USA

9 Department of Medicine, Atherosclerosis and Vascular Medicine, Baylor College of Medicine, Houston TX, USA

10 Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC, USA

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BMC Endocrine Disorders 2010, 10:9 doi:10.1186/1472-6823-10-9

Published: 17 May 2010

Additional files

Additional file 1:

Power Analysis for the estimation of association between TCF7L2 rs7903146 and retinal microvasculature in the ARIC Study. Additional file 1 contains three supplementary figures on the power analyses performed for the estimation of association between TCF7L2 rs7903146 and retinal microvasculature in the ARIC Study.

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