Light microscopy photomicrographs of the stroma underneath the sensory epithelia (SE) of patients with Meniere's disease. (A) Empty spaces within the stroma, resembling vacuolization or interstitial edema, were seen in the utricular stroma from Meniere's vestibular endorgans (arrows). NF showed almost normal appearance (NF). (B) The utricular stroma from another patient with Meniere's disease showing intercellular spaces (asterisks) and pronounced vacuolar structures (arrows). Bar in A and B = 35 μm. Two-micron thin sections counterstained with osmium tetroxide and toluidine blue.
McCall et al. BMC Ear, Nose and Throat Disorders 2009 9:4 doi:10.1186/1472-6815-9-4