Table 1 |
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Genotype distribution of PAI-1 polymorphism in SSNHL and controls | |||||||
Model | Genotype | Controls, n = 113 (Frequency) | SSNHL, n = 103 (Frequency) | OR | 95 % CI | χ^{2} | p value |
Co-dominant | 4 G/5 G | 50 (44.2 %) | 63 (61.2 %) | 1 | |||
4 G/4 G | 29 (25.7 %) | 24 (23.3 %) | 0.66 | 0.34 – 1.27 | 1.59 | 0.210 | |
5 G/5 G | 34 (30.1 %) | 16 (15.5 %) | 0.37 | 0.19 - 0.75 | 7.83 | 0.005 | |
Recessive | 4 G/4 G-4 G/5 G | 79 (69.9 %) | 87 (84.5 %) | 1 | |||
5 G/5 G | 34 (30.1 %) | 16 (15.5 %) | 0.43 | 0.22 - 0.83 | 6.42 | 0.011 |
SSNHL sudden sensorineural hearing loss; Odds ratios (OR) with 95 % confidence intervals (CI) and results (p values) of χ^{2} analysis (chi-square test) were calculated for genotype frequencies compared with control.
Cho et al.
Cho et al. BMC Ear, Nose and Throat Disorders 2012 12:5 doi:10.1186/1472-6815-12-5