Table 2

Effect of HA1 polymorphisms on the amplitudes corresponding to IS frequencies F(0.055) and F(0.295).

Mutation

ΔA [F(0.055)]

(%)

ΔA [F(0.295)]

(%)

Propensity for human interaction pattern


R36K*

-7.5

+5.0

+

L61I

0

0

0

F71S

-1.2

+0.4

+

N97D

-6.6

-9.1

±

T128S

-1.4

+1.2

+

R130K

-5.1

-5.0

±

R146K

-7.5

-2.9

±

N168D*

+4.9

-4.8

-

T216I*

-5.7

+10.5

+

A224E

0

0

0

S271P*

-4.3

+2.7

+

V298I

0

0

0

E302K

-3.9

+1.7

+

M314L

-3.6

+6.5

+


Mutations present in swine H1N1/N2 strains which infect humans are marked with asterisk.

Veljkovic et al. BMC Structural Biology 2009 9:62   doi:10.1186/1472-6807-9-62

Open Data