The crystal structure of Haloferax volcanii proliferating cell nuclear antigen reveals unique surface charge characteristics due to halophilic adaptation
1 Institute of Genetics, University of Nottingham, Queen's Medical Centre, Nottingham, NG7 2UH, UK
2 Current address: Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
BMC Structural Biology 2009, 9:55 doi:10.1186/1472-6807-9-55Published: 22 August 2009
Additional file 1:
Figure S1 – Electrostatic surfaces of classical PCNAs. Figure S2 – Sodium ion binding at a crystal packing interface. Table S1 – Interactions at the monomer-monomer interface. Table S2 – Amino acid usage in PCNAs. Table S3 – B factor analysis. Tables S4 and S5 – Na+ coordination distances.
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Animation demonstrating the reduction in electrostatic potential in the HvPCNA pore.
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