Figure 3.

B-RAFV600E. A) The conformation of B-RAFV600E after 15 ns of simulation time. The part of the A-loop resolved in the crystal structure (A-loop1) and the modelled portion (A-loop2) are shown. B) A close look at the conformation of the major catalytic residues and the identified hydrogen bond network in the unbounded B-RAFV600E after 15 ns of simulation time. The dotted lines and the adjacent values represent the H-bonds and their distances.

Fratev and Jónsdóttir BMC Structural Biology 2009 9:47   doi:10.1186/1472-6807-9-47
Download authors' original image