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Type II restriction endonuclease R.Hpy188I belongs to the GIY-YIG nuclease superfamily, but exhibits an unusual active site

Katarzyna H Kaminska, Mikihiko Kawai, Michal Boniecki, Ichizo Kobayashi and Janusz M Bujnicki*

BMC Structural Biology 2008, 8:48  doi:10.1186/1472-6807-8-48