Table 1

Characteristics of loop generation techniques

Technique

Loop closure

Prior distribution/energy function

Global search

Scalability


Optimization

Exact

Y

N

+

Inverse kinematics sampling

Exact

N

Y

++

Discrete search

Inexact

Y

Finite subset

-

Standard Monte Carlo

No

Y

Y, reqs. mixing

+

SLIKMC

Exact

Y

Y, reqs. mixing

++


Zhang and Hauser BMC Structural Biology 2013 13(Suppl 1):S9   doi:10.1186/1472-6807-13-S1-S9

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