Mixing of SLIKMC samples. Sampling conformations of a planar 20-link chain, anchored at the endpoints, with a uniform prior. Left: starting from a deliberately bad initial conformation. Middle: the sequence mixes relatively quickly, but the first 40 samples are biased by the initial conformation and autocorrelate strongly. Right: a sequence that takes every 40'th sample does not significantly autocorrelate.
Zhang and Hauser BMC Structural Biology 2013 13(Suppl 1):S9 doi:10.1186/1472-6807-13-S1-S9