Pairwise sequence alignment between ISDR (Interferon sensitivity determining region) of NS5A and PKR dimerisation region. Some of the residues involved in dimerisation of PKR are highlighted in magenta. Equivalent residues in NS5A are highlighted in cyan. Non equivalent residue in NS5A is highlighted in green. The equivalent position for dimer interface residue V is not marked in NS5A sequence because this position is highly variable.
Sudha et al. BMC Structural Biology 2012 12:28 doi:10.1186/1472-6807-12-28