The number of superfamily agreements/disagreements with SCOP for varying confidence values. A ROC curve showing the number of superfamilies containing agreements against the number containing disagreements of trees with SCOP's groupings, for confidence values decreasing from left to right. For sequence trees, confidence is based on the bootstrap value assigned to an edge. Structures are ranked using the total structural distance, and function is ranked by the total number of GO terms or EC numbers which support an edge.
Pethica et al. BMC Structural Biology 2012 12:27 doi:10.1186/1472-6807-12-27