Figure 8.

Putative ligand binding pocket at the dimeric interface of St AckA. (A) Representation of the A-subunit (yellow except for the variable segment shown in bright-orange) of Form-II StAckA with the bound citrate (CIT-501, pink, ball and stick model) indicating the location of the cavity observed at the dimeric interface. Secondary structures corresponding to the variable segments are labeled. (B) A similar surface representation of the B-subunit (cyan with variable segment highlighted in blue) of Form-II StAckA. (C) Dimeric interface pocket in Form-I StAckA. A- and B-subunits of Form-I StAckA are shown in green and red, respectively. Active site cavity of each subunit is shown. Dimeric interface pocket is highlighted using spheres

Chittori et al. BMC Structural Biology 2012 12:24   doi:10.1186/1472-6807-12-24
Download authors' original image