Figure 4.

Tyk2 sequence variation enables novel crystal contacts.a: Sequence alignment of human and mouse Tyk2 using CLUSTALW [38]. The residues highlighted in the red box are the glycine rich loop. b: Location of mouse Tyk2 surface residue Gly928 (Asp935 in human Tyk2) permits a close, van der Waals crystal contact. (Picture generated with COOT) [36].

Argiriadi et al. BMC Structural Biology 2012 12:22   doi:10.1186/1472-6807-12-22
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