Table 1

Data set.

PDB^a)

Q^b)

Organism^c)

[NaCl]^d)

Survival^e)

Res(Å)^f)

Name^g)

PDB^a)

Q^b)

Organism^c)

Res(Å)^f)

Sequence identity(%)^h)

1

1DOI

1

Haloarcula marismortui (A)

3.4-3.9M

Salt-in

1.90

Ferredoxin

1FXA

1

Anabaena sp. (B)

2.50

51%

2

1NWZ

1

Halorhodospira halophila (B)

1.5-5.1M

Osmolytes

0.82

Photoreceptor

1MZU

1

Rhospirillum centenum (B)

2.00

46%

3

1TJO

12

Halobacterium salinarum (A)

3.9M

Salt-in

1.60

DNA-protecting protein

2VXX

12

Thermosinechococcus elongatus (B)

2.40

36%

4

2B5W

2

Haloferax mediterranei (A)

3.4-4.3M

Salt-in

1.60

Glucose dehydrogenase

2CD9

4

Sulfolobus solfatarius (A)

1.80

30%

5

2CC6

12

Halobacterium salinarum (A)

3.9M

Salt-in

1.27

Dodecin

2V18

12

Thermus thermophilus (B)

2.59

42%

6

3IBM

2

Halorhodospira halophila (B)

1.5-5.1M

Osmolytes

2.00

Cupin 2 domain-containing protein

3KGZ

2

Rhodopseudomonas palustris (B)

1.85

44%

7

1ITK

2

Haloarcula marismortui (A)

3.4-3.9M

Salt-in

2.00

Catalase-peroxidase

2FXG

2

Burkolderia pseudomallei (B)

2.00

60%

8

2AZ3

6

Halobacterium salinarum (A)

3.9M

Salt-in

2.20

Nucleoside diphosphate kinase

3B54

6

Saccharomyces cerevisiae (B)

3.10

54%

9

2J5K

4

Haloarcula marismortui (A)

3.4-3.9M

Salt-in

1.95

Malate dehydrogenase

1Y6J

2

Clostridium thermocellum (B)

3.01

33%

10

1CNO

2

Marinobacter hydrocarbonoclasticus (B)

0.6-0.85M

Osmolytes

2.20

Cytochrome c₅₅₂

1ETP

1

Pseudomonas stutzeri (B)

2.20

47%

11

1NML

1

Marinobacter hydrocarbonoclasticus (B)

0.6-0.85M

Osmolytes

2.20

Cytochrome c peroxidase

3HQ6

2

Geobacter sulfurreducens (B)

2.20

64%

12

2VPN

1

Halomonas elongata (B)

0.5-1.4 max 5.5M

Osmolytes

1.55

Prisplasmic ectoin-binding protein

3FXB

1

Ruegeria pomeroyi (B)

2.90

62%

13

3IFV

3

Haloferax volcanii (A)

1.7M

Salt-in

2.00

Proliferating cell nuclear antigen

1RWZ

3

Archaeglobus fulgidus (A)

1.80

36%

14

3IGN

1

Marinobacter aquaeloi vt8 (B)

0.6-0.85M

Osmolytes

1.83

GGDEF domain

3I5C

2

Pseudomonas aeruginosa pao1 (B)

1.94

40%

15

3BSM

8

Chromohalobacter salexigens (B)

1.2-1.7M

Osmolytes

2.20

D-mannonate dehydratase

2QJJ

8

Novosphingobium aromaticivorans (B)

1.80

66%

List of protein pairs utilized in the work. Boldfaced PDB codes indicate extreme halophiles.

^a) Protein Data Bank code

^b) Number of monomers in the biological unit

^c) Source organisms. (A) = Archaea; (B) = Bacteria

^d) Optimal range of NaCl concentration for growth. The first 9 lines contain structures from extreme halophiles; the remaining 6 lines report moderate halophiles.

^e) The survival strategy adopted by corresponding organism: "salt-in" or "osmolytes" strategy

^f) Crystallographic resolution

^g) Protein name as reported in the Protein Data Bank

^h) Sequence percentage of identity between protein pairs

Siglioccolo et al. BMC Structural Biology 2011 11:50   doi:10.1186/1472-6807-11-50