Identification of functionally annotated residues as a function of the reverse template E-value. Histogram showing the relationship between the E-value of the reverse template hit and how often it matches a functionally annotated residue in the matched structure. The bars show: the number of times one of the matched residues was functionally annotated (coloured), the number of times none were annotated (black), and the number of time the matched structure had no annotation whatsoever (white). The colours correspond to the 'confidence class' of the reverse template hit, which is determined by its E-value: red = certain match (E < 10-6); pink = probable match (10-6 < E < 10-2); orange = possible match (10-2 < E < 10-1); and blue = long shot (10-1 < E < 10).
Lee et al. BMC Structural Biology 2011 11:2 doi:10.1186/1472-6807-11-2