Table 1

t-tests of sequence percent compositions of mesophilc, thermophilic, and hyperthermophilic proteins.

A

C

D

E

F

G

H

I

K

L

mean_comp_meso:

8.26

1.92

5.80

6.53

3.85

7.29

2.29

5.48

6.22

8.86

sd_comp_meso:

4.31

3.05

2.22

3.02

1.89

3.08

1.53

2.52

3.38

3.52

mean_comp_therm:

10.05

0.78

5.13

8.32

3.62

8.30

2.15

4.80

4.77

10.26

sd_comp_therm:

3.48

1.23

2.29

2.87

1.45

2.12

1.18

3.04

2.29

3.87

t_therm_wrt_meso:

6.03

-9.08

-3.57

7.49

-1.83

5.42

-1.35

-2.72

-7.21

4.40

mean_comp_hyper:

7.26

0.78

5.20

10.05

4.07

7.17

1.64

7.73

8.50

9.10

sd_comp_hyper:

2.95

1.05

1.76

2.51

1.64

2.23

1.05

2.44

2.60

2.39

t_hyper_wrt_meso:

-4.09

-10.19

-4.17

17.47

1.72

-0.65

-7.37

11.72

10.74

1.21

t_therm_wrt_hyp:

7.99

0.00

-0.32

-5.93

-2.71

4.83

4.22

-9.80

-14.19

3.30

M

N

P

Q

R

S

T

V

W

Y

mean_comp_meso:

2.17

4.51

4.52

4.04

4.79

6.07

5.62

6.90

1.43

3.44

sd_comp_meso:

1.58

2.30

2.91

2.07

2.62

2.61

2.51

2.62

1.25

1.95

mean_comp_therm:

1.87

3.19

5.43

2.69

6.82

4.07

4.74

8.42

1.31

3.30

sd_comp_therm:

1.11

2.29

2.05

1.59

2.81

2.13

2.34

2.36

1.16

1.71

t_therm_wrt_meso:

-3.14

-6.94

5.10

-9.87

8.77

-11.07

-4.52

7.65

-1.20

-1.00

mean_comp_hyper:

2.11

3.49

4.02

1.80

5.56

4.51

4.00

8.44

1.02

3.56

sd_comp_hyper:

1.14

1.62

1.57

1.16

2.27

1.72

1.48

2.28

1.07

1.71

t_hyper_wrt_meso:

-0.59

-7.65

-3.60

-22.12

4.23

-10.82

-12.71

8.45

-4.78

0.87

t_therm_wrt_hyp:

-1.98

-1.39

7.11

5.88

4.55

-2.10

3.46

-0.08

2.41

-1.41


t-tests of sequence percent compositions of mesophilc, thermophilic, and hyperthermophilic proteins Amino acids significantly over-represented in hyperthermophiles with respect to mesophiles are: Glu, Ile, Lys, Arg, and Val. Amino acids significantly under-represented in hyperthermophiles with respect to mesophiles are: Ala, Cys, Asp, His, Asn, Pro, Gln, Ser, Thr, and Trp. Amino acids significantly over-represented in thermophiles with respect to mesophiles are: Ala, Glu, Gly, Leu, Pro, Arg, and Val. Amino acids significantly under-represented in thermophiles with respect to mesophiles are: Cys, Asp, Lys, Met, Asn, Gln, Ser, and Thr. Amino acids significantly over-represented in hyperthermophiles with respect to thermophiles are: Glu, Ile, and Lys. Amino acids significantly under-represented in hyperthermophiles with respect to thermophiles are: Ala, Gly, His, Leu, Pro, Gln, Arg, and Thr. These statistics were tabulated from nonredundant sets of 184 hyperthermophilic structures (45419 residues), 162 thermophilic structures (41470 residues), and 1262 mesophilic structures (269799 residues).

Taylor and Vaisman BMC Structural Biology 2010 10(Suppl 1):S5   doi:10.1186/1472-6807-10-S1-S5

Open Data