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Open Access Highly Accessed Research article

Forced unbinding of GPR17 ligands from wild type and R255I mutant receptor models through a computational approach

Chiara Parravicini, Maria P Abbracchio*, Piercarlo Fantucci and Graziella Ranghino

BMC Structural Biology 2010, 10:8  doi:10.1186/1472-6807-10-8

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abstract correction

Chiara Parravicini   (2010-05-20 15:41)  University of Milan email

Please note that the abstract contains a nonsense in the Conclusions section that should correctly read as follows:

Conclusions: These data thus suggest that, in contrast to what has been hypothesized for nucleotides, the lack of the R255 residue doesn't affect the binding of pranlukast. Aromatic interactions are instead likely to play a predominant role in the recognition of pranlukast, suggesting that two different binding subsites are present on GPR17.

Competing interests

None declared

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