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Open Access Highly Accessed Methodology article

Improving predicted protein loop structure ranking using a Pareto-optimality consensus method

Yaohang Li1*, Ionel Rata2, See-wing Chiu2 and Eric Jakobsson2

Author Affiliations

1 Department of Computer Science, Old Dominion University, Norfolk, VA 23529, USA

2 Department of Molecular and Integrative Physiology, Department of Biochemistry, UIUC Programs in Biophysics, Neuroscience, and Bioengineering, National Center for Supercomputing Applications, and Beckman Institute, University of Illinois, Urbana, IL 61801, USA

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BMC Structural Biology 2010, 10:22  doi:10.1186/1472-6807-10-22

Published: 20 July 2010

Additional files

Additional file 1:

Efficiency of POC in Identifying the Native Structures. The supplementary file describes the efficiency of the POC method with the native structure mixed in the decoy sets generated by Jacobson et al. The POC method also leads to less false positives compared to individual scoring functions.

Format: DOCX Size: 157KB Download file

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