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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Matthew Kaiser PhD
Welcome to BMC Structural Biology published by BioMed Central
BMC Structural Biology is an open access journal publishing original peer-reviewed research articles in investigations into the structure of biological macromolecules, including solving structures, structural and functional analyses, and computational modeling.
BMC Structural Biology (ISSN 1472-6807) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Structural Biology 2009, 9 :28
Using an optimal linear combination of six leading threading programs, a novel programming model for protein structure refinement increases the accuracy of inter-residue contact prediction and offers a significant improvement over traditional consensus methods.
BMC Structural Biology 2009, 9 :26
A new method validates the premise that low protein sequence conservation and unaligned sequences indicate an intrinsically disordered (ID) structure, and is used to achieve a more accurate identification of ID regions in human transcription factors.
BMC Structural Biology 2009, 9 :23
A new consistent benchmark set reduces errors in protein structure prediction and comparison, which occur when using the SCOP and CATH databases due to large differences in their domain definitions and fold space partitioning.
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Research article
Large-scale evaluation of dynamically important residues in proteins predicted by the perturbation analysis of a coarse-grained elastic model Wenjun Zheng, Mustafa Tekpinar BMC Structural Biology 2009, 9 :45 (10 [Abstract ] [Provisional PDF ]
Research article
Amyloidogenic determinants are usually not buried Kimon K Frousios, Vassiliki A Iconomidou, Carolina-Maria Karletidi, Stavros J Hamodrakas BMC Structural Biology 2009, 9 :44 (9 [Abstract ] [Provisional PDF ]
Research article
Exon 6 of human JAG1 encodes a conserved structural unit Alessandro Pintar, Corrado Guarnaccia, Somdutta Dhir, Sandor Pongor BMC Structural Biology 2009, 9 :43 (8 [Abstract ] [Provisional PDF ]
Research article
Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases
Apirat Chaikuad, R. Leo Brady BMC Structural Biology 2009, 9 :42 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Improved estimation of structure predictor quality Kevin W DeRonne, George Karypis BMC Structural Biology 2009, 9 :41 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Structural and Phylogenetic Analysis of a Conserved Actinobacteria-Specific Protein (ASP1; SCO1997) from Streptomyces coelicolor
Beile Gao, Seiji Sugiman-Marangos, Murray S Junop, Radhey S Gupta BMC Structural Biology 2009, 9 :40 (10 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Modelling substrate specificity and enantioselectivity for lipases and esterases by substrate-imprinted docking P Benjamin Juhl, Peter Trodler, Sadhna Tyagi, J BMC Structural Biology 2009, 9 :39 (3 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Modeling of solvent-dependent conformational transitions in Burkholderia cepacia lipase Peter Trodler, Rolf D Schmid, J BMC Structural Biology 2009, 9 :38 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Analysis of proteins with the 'hot dog' fold: Prediction of function and identification of catalytic residues of hypothetical proteins Lakshmi S Pidugu, Koustav Maity, Karthikeyan Ramaswamy, Namita Surolia, Kaza Suguna BMC Structural Biology 2009, 9 :37 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF Meiying Zheng, Tomasz Cierpicki, Ko Momotani, Mykhaylo V Artamonov, Urszula Derewenda, John H Bushweller, Avril V Somlyo, Zygmunt S Derewenda BMC Structural Biology 2009, 9 :36 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Iterative refinement of structure-based sequence alignments by Seed Extension Changhoon Kim, Chin-Hsien Tai, Byungkook Lee BMC Bioinformatics 2009, 10 :210 (9 [Abstract ] [Provisional PDF ]
Methodology article
ResBoost: characterizing and predicting catalytic residues in enzymes Ron Alterovitz, Aaron Arvey, Sriram Sankararaman, Carolina Dallett, Yoav Freund, Kimmen Sjolander BMC Bioinformatics 2009, 10 :197 (27 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Ab initio and homology based prediction of protein domains by recursive neural networks Ian Walsh, Alberto JM Martin, Catherine Mooney, Enrico Rubagotti, Alessandro Vullo, Gianluca Pollastri BMC Bioinformatics 2009, 10 :195 (26 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Theoretical study of the Usutu virus helicase 3D structure, by means of computer-aided homology modelling Dimitrios Vlachakis Theoretical Biology and Medical Modelling 2009, 6 :9 (25 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Characterization and structural analysis of wild type and a non-abscission mutant at the development funiculus (Def) locus in Pisum sativum L. Kwadwo OWUSU Ayeh, YeonKyeong Lee, Mike J Ambrose, Anne Kathrine Hvoslef-Eide BMC Plant Biology 2009, 9 :76 (23 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Reproducibility and repeatability of measuring the electrical impedance of the pregnant human cervix-the effect of probe size and applied pressure Roobin P Jokhi, Vidita V Ghule, Brian H Brown, Dilly OC Anumba BioMedical Engineering OnLine 2009, 8 :10 (17 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Structural motifs recurring in different folds recognize the same ligand fragments Gabriele Ausiello, Pier Federico Gherardini, Elena Gatti, Ottaviano Incani, Manuela Helmer-Citterich BMC Bioinformatics 2009, 10 :182 (15 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Epistatic interactions modulate the evolution of mammalian mitochondrial respiratory complex components Luisa Azevedo, Joao Carneiro, Barbara van Asch, Ana Moleirinho, Filipe Pereira, Antonio Amorim BMC Genomics 2009, 10 :266 (13 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
TOMOBFLOW: feature-preserving noise filtering for electron tomography Jose-Jesus Fernandez BMC Bioinformatics 2009, 10 :178 (12 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Combining specificity determining and conserved residues improves functional site prediction Olga V Kalinina, Mikhail S Gelfand, Robert B Russell BMC Bioinformatics 2009, 10 :174 (9 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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