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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Tim Sands PhD
Welcome to BMC Structural Biology published by BioMed Central
BMC Structural Biology is an open access journal publishing original peer-reviewed research articles in investigations into the structure of biological macromolecules, including solving structures, structural and functional analyses, and computational modeling.
BMC Structural Biology (ISSN 1472-6807) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Structural Biology 2009, 9 :68
Biologically meaningful subfamilies of protein domains and functional residues can be predicted using an extension of the context-specific independence mixture clustering method which implements a partially-supervised learning approach to integrate experimental data.
BMC Structural Biology 2009, 9 :65
Changes in hydrophobic interactions at low temperatures favour a more open conformation of Esherichia coli tryptophanase, promoting release of the cofactor pyridoxal phosphate, which leads to dissociation of the tetramer into dimers.
BMC Structural Biology 2009, 9 :62
Comparing electron-ion interaction potentials of amino acids in pandemic H1N1 hemagglutinin against those of non-pandemic H1N1/N2 reveals four mutations that seem critical for increased interaction with human proteins, and three sites where mutations will probably increase human infectivity.
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Research article
Discriminating the native structure from decoys using scoring functions based on the residue packing in globular proteins Ranjit PRASAD Bahadur, Pinak Chakrabarti BMC Structural Biology 2009, 9 :76 (28 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
The structure of pyogenecin immunity protein, a novel bacteriocin-like immunity protein from Streptococcus pyogenes Changsoo Chang, Penny Coggill, Alex Bateman, Robert D Finn, Marcin Cymborowski, Zbyszek Otwinowski, Wladek Minor, Lour Volkart, Andrzejj Joachimiak BMC Structural Biology 2009, 9 :75 (17 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Solution structure of the Equine Infectious Anemia Virus p9 protein: a rationalization of its different ALIX binding requirements compared to the analogous HIV-p6 protein Alok Sharma, Karsten Bruns, Rene Roder, Peter Henklein, Jorg Votteler, Victor Wray, Ulrich Schubert BMC Structural Biology 2009, 9 :74 (17 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
TIM-Finder: A new method for identifying TIM-barrel proteins Jing-Na Si, Ren-Xiang Yan, Chuan Wang, Ziding Zhang, Xiao-Dong Su BMC Structural Biology 2009, 9 :73 (14 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Prediction of calcium-binding sites by combining loop-modeling with machine learning Tianyun Liu, Russ B Altman BMC Structural Biology 2009, 9 :72 (11 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Splitting statistical potentials into meaningful scoring functions: Testing the prediction of near-native structures from decoy conformations Patrick Aloy, Baldo Oliva BMC Structural Biology 2009, 9 :71 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The structural and functional determinants of the Axin and Dishevelled DIX domains Matthias T Ehebauer, Alfonso Martinez Arias BMC Structural Biology 2009, 9 :70 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Software
Interacting with the biomolecular solvent accessible surface via a haptic feedback device Matthew B Stocks, Steven Hayward, Stephen D Laycock BMC Structural Biology 2009, 9 :69 (27 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Partially-supervised protein subclass discovery with simultaneous annotation of functional residues Benjamin Georgi, J BMC Structural Biology 2009, 9 :68 (26 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Structural insights into the substrate tunnel of Saccharomyces cerevisiae carbonic anhydrase Nce103 Yan-Bin Teng, Yong-Liang Jiang, Yong-Xing He, Wei-Wei He, Fu-Ming Lian, Yuxing Chen, Cong-Zhao Zhou BMC Structural Biology 2009, 9 :67 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
FlexSnap: Flexible Non-sequential Protein Structure Alignment. Saeed Salem, Mohammed J. Zaki, Chris Bystroff Algorithms for Molecular Biology 2010, 5 :12 (4 [Abstract ] [Provisional PDF ]
Research
Linear-time protein 3-D structure searching with insertions
and deletions Tetsuo Shibuya, Jesper Jansson, Kunihiko Sadakane Algorithms for Molecular Biology 2010, 5 :7 (4 [Abstract ] [Provisional PDF ]
Research article
A genomic glimpse of aminoacyl-tRNA synthetases in malaria parasite Plasmodium falciparum Tarun KUMAR Bhatt, Charu Kapil, Sameena Khan, Mohamad AMAN Jairajpuri, Vinay Sharma, Daniele Santoni, Francesco Silvestrini, Elisabetta Pizzi, Amit Sharma BMC Genomics 2009, 10 :644 (31 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Review
Tuning microbial hosts for membrane protein production Maria Freigassner, Harald Pichler, Anton Glieder Microbial Cell Factories 2009, 8 :69 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
3PD: Rapid design of optimal primers for chromosome conformation capture assays Sebastian Frohler, Christoph Dieterich BMC Genomics 2009, 10 :635 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
LipocalinPred: a SVM-based method for prediction of lipocalins Jayashree Ramana, Dinesh Gupta BMC Bioinformatics 2009, 10 :445 (24 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
svmPRAT: SVM-based Protein Residue Annotation Toolkit Huzefa Rangwala, Christopher Kauffman, George Karypis BMC Bioinformatics 2009, 10 :439 (22 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Primary ciliogenesis defects are associated with human astrocytoma/ glioblastoma cells Joanna J. Moser, Marvin J. Fritzler, Jerome B. Rattner BMC Cancer 2009, 9 :448 (17 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Modular prediction of protein structural classes from sequences of twilight-zone identity with predicting sequences Marcin J Mizianty, Lukasz Kurgan BMC Bioinformatics 2009, 10 :414 (13 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Time dependence of changes of two cartilage layers in anterior cruciate ligament insertion after resection on chondrocyte apoptosis and decrease in glycosaminoglycan Masataka Sakane, Hirotaka Mutsuzaki, Shinya Hattori, Hiromi Nakajima, Naoyuki Ochiai Sports Medicine, Arthroscopy, Rehabilitation, Therapy & Technology 2009, 1 :27 (10 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
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