Table 5

Locomotor tests
AGE PROCEDURE ANOVA ON THE RANKS
CONTROL CRUSH DAP5 CRUSH-DAP5 P-VALUE
Rotarod (sec) P14 264.20 ± 12.28 8.40 ± 2.70* 256.00 ± 12.02 19.00 ± 3.39 # 0.001
P21 289.80 ± 14.94 20.40 ± 6.50* 276.40 ± 16.02 51.40 ± 7.86# 0.001
P28 289.20 ± 11.80 37.20 ± 9.15* 290.60 ± 12.92 104.20 ± 9.98# 0.001
ADULT 285.80 ± 13.57 45.80 ± 7.98* 289.40 ± 15.03 229.80 ± 12.34# 0.001
Bridge 1 cm P14 1.20 ± 0.45 8.60 ± 0.55* 1.00 ± 0.71 4.20 ± 0.84# 0.001
P21 0.80 ± 0.84 7.40 ± 0.89* 0.60 ± 0.55 2.60 ± 1.52 0.003
P28 0.80 ± 0.84 7.20 ± 0.84* 1.00 ± 0.71 2.80 ± 0.45# 0.001
ADULT 0.80 ± 0.45 6.20 ± 1.10* 0.80 ± 0.45 3.00 ± 0.71# 0.001
Bridge 3 cm P14 0.80 ± 0.84 7.60 ± 0.89* 0.60 ± 0.55 2.80 ± 0.84# 0.001
P21 0.40 ± 0.89 7.00 ± 0.71* 0.40 ± 0.55 2.80 ± 0.84# 0.001
P28 0.60 ± 0.55 5.80 ± 1.30* 0.60 ± 0.89 2.20 ± 0.84# 0.002
ADULT 0.20 ± 0.45 5.00 ± 1.58* 0.60 ± 0.55 2.20 ± 0.84# 0.001
Bridge 5 cm P14 0.60 ± 0.55 6.20 ± 0.45* 0.00 ± 0.00 2.40 ± 0.55# 0.001
P21 0.40 ± 0.55 4.40 ± 1.14* 0.40 ± 0.55 1.60 ± 1.14 0.004
P28 0.40 ± 0.55 4.40 ± 1.14* 0.20 ± 0.45 2.00 ± 1.00# 0.001
ADULT 0.00 ± 0.00 2.80 ± 0.84* 0.20 ± 0.45 1.80 ± 0.84* 0.001
Gait 1 cm P14 2.80 ± 0.84 4.60 ± 0.89* 2.60 ± 1.14 3.40 ± 0.89 0.037
(errors) P21 2.40 ± 1.14 4.60 ± 0.55* 2.20 ± 1.48 3.00 ± 0.71 0.016
P28 2.80 ± 0.84 3.80 ± 0.84 2.40 ± 1.14 2.60 ± 0.89 0.149
ADULT 2.40 ± 1.14 4.00 ± 1.00 2.00 ± 1.58 2.00 ± 1.22 0.091
Gait 3 cm P14 2.40 ± 0.89 4.00 ± 0.71* 2.20 ± 0.84 2.80 ± 1.10 0.025
(errors) P21 1.80 ± 0.84 3.80 ± 0.84* 1.80 ± 1.30 1.80 ± 1.30 0.036
P28 1.80 ± 1.48 4.20 ± 0.84* 1.60 ± 0.89 2.00 ± 0.00 0.014
ADULT 1.80 ± 1.30 3.80 ± 1.30 1.60 ± 1.14 1.80 ± 1.30 0.094
Gait 5 cm P14 2.40 ± 1.52 3.40 ± 0.55 1.60 ± 1.14 3.00 ± 1.00 0.098
(errors) P21 1.40 ± 1.14 3.00 ± 0.71* 0.80 ± 0.84 1.40 ± 0.55 0.019
P28 1.80 ± 1.48 3.60 ± 0.89* 1.80 ± 0.45 1.20 ± 1.30 0.029
ADULT 1.20 ± 1.30 3.40 ± 1.52 1.20 ± 0.84 1.20 ± 0.84 0.089
Limb Rotation P14 13.40 ± 0.98 0.00 ± 0.00 13.18 ± 0.76 14.42 ± 0.89 0.194
P21 17.88 ± 0.44 21.24 ± 0.86* 17.90 ± 0.53 20.00 ± 0.83* 0.002
P28 18.62 ± 1.21 22.56 ± 0.79* 18.50 ± 0.86 22.12 ± 0.79* 0.002
ADULT 20.76 ± 1.87 27.28 ± 0.56* 20.62 ± 1.64 24.60 ± 0.72# 0.001
Stride Length (cm) P14 3.78 ± 0.53 0.00 ± 0.00 3.70 ± 0.29 2.30 ± 0.51* 0.010
P21 11.86 ± 0.56 9.94 ± 0.44* 12.02 ± 0.57 10.10 ± 0.70* 0.003
P28 15.78 ± 1.18 13.56 ± 0.41* 15.42 ± 1.19 13.76 ± 0.60* 0.006
ADULT 17.82 ± 0.68 13.14 ± 0.95* 18.02 ± 0.51 16.44 ± 0.54# 0.001
DBF(cm) P14 0.98 ± 0.18 0.00 ± 0.00 0.98 ± 0.22 0.64 ± 0.13* 0.027
P21 1.86 ± 0.18 1.30 ± 0.19* 2.02 ± 0.20 1.36 ± 0.13* 0.002
P28 2.70 ± 0.19 2.96 ± 0.11 2.78 ± 0.16 2.20 ± 0.14* 0.003
ADULT 3.34 ± 0.23 3.80 ± 0.19* 3.43 ± 0.19 2.92 ± 0.16# 0.003

Values are expressed as Mean ± Standard deviation. Post-hoc multiple comparisons. *: different from control. #: different from crush. Level of significance was a = 0.05.

Petsanis et al.

Petsanis et al. BMC Physiology 2012 12:5   doi:10.1186/1472-6793-12-5

Open Data