Table 2

Enriched biological processes showing dysregulation in zebrafish and mammalian obesity

Zebrafish

Rat

Mouse

Human


Process

NES

MC

p-value

NES

MC

p-value

NES

MC

p-value

NES

MC

p-value


Blood coagulation

2.3

3.1

0.0E+0

2.0

1.1

0.0E+0

1.7

1.1

9.5E-3

1.8

1.5

0.0E+0


Platelet activation

2.0

4.8

0.0E+0

1.8

1.1

6.1E-3

1.7

1.0

1.9E-2


Fatty acid metabolism

2.2

1.6

0.0E+0

1.8

1.0

0.0E+0

1.8

1.0

4.5E-3


Cholesterol efflux

1.6

1.1

0.0E+0

1.9

1.4

5.7E-3

1.8

1.3

0.0E+0


Triglyceride metabolism

1.8

2.0

0.0E+0

1.8

1.2

5.8E-3

1.7

1.1

9.5E-3


NES: normalized enrichment score; MC: median change in gene expression in the gene set

Oka et al. BMC Physiology 2010 10:21   doi:10.1186/1472-6793-10-21

Open Data