Table 4 |
|||
|
Clusters of metabolic drug scopes in the human irreversible network. |
|||
|
Cluster Id |
Number of drugs in cluster |
Average scope size |
Significant compounds in consensus scope |
|
|
|||
|
I |
62 |
8 |
- |
|
II |
24 |
10 |
- |
|
III |
85 |
230 |
ATP, Pyruvate, Galactose |
|
IV |
35 |
40 |
Arachidonate |
|
V |
14 |
11 |
- |
|
VI |
15 |
21 |
- |
|
VII |
13 |
27 |
- |
|
VIII |
5 |
110 |
Pyruvate |
|
IX |
8 |
21 |
- |
|
X |
1 |
12 |
CoA |
|
XI |
1 |
25 |
CoA |
|
XII |
2 |
53 |
Tryptophan |
|
XIII |
3 |
21 |
- |
|
XIV |
2 |
14 |
- |
|
XV |
1 |
16 |
- |
|
XVI |
2 |
11 |
- |
|
XVII |
1 |
24 |
- |
|
XVIII |
1 |
30 |
Tyrosine |
|
XIX |
1 |
16 |
- |
|
|
|||
|
Schwartz and Nacher BMC Chemical Biology 2009 9:4 doi:10.1186/1472-6769-9-4 |
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