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Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue

Patrick Chène†, Joëlle Rudloff†, Joseph Schoepfer, Pascal Furet, Peter Meier, Zhiyan Qian, Jean-Marc Schlaeppi, Rita Schmitz and Thomas Radimerski*

BMC Chemical Biology 2009, 9:1 doi:10.1186/1472-6769-9-1

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