Figure 4.

(A): Electrophoretogram for the incubated mixtures of pBR322 plasmid DNA and varying concentrations of cisplatin (lanes 0–5: 0: untreated plasmid; 1: 0, 2: 1 μM; 3: 2.5 μM; 4: 5 μM; 5: 10 μM) and transplatin (lanes 7–13: 7: untreated plasmid; 8: 0, 9: 1 μM; 10: 2.5 μM; 11: 5 μM; 12: 10 μM) (B): Electrophoretogram for the incubated mixtures of pBR322 plasmid DNA and varying concentrations of: AH3 and AH7 (lane 0: untreated and undigested DNA, lane 1: 5 μM, lane 2: 10, lane 3: 15 μM, lane 4: 20 μM, lane 5: 25 μM, lane 6: 30 μM, lane 7: 35 μM, lane 8: 40 μM, lane 9: 45 μM, lane 10: 50 μM) followed by digestion with BamH1. Lane B applies to untreated but digested pBR322 plasmid DNA.