Figure 5.

Immunoblot analyses showing suppression of total cellular STAT1 (selected novel hit from Table 5) as well as activated nuclear pSTAT1 in response to PEO treatments in LPS-activated mouse macrophage. Cells were pre-treated with PEO for 2 h prior to 45 min LPS-activation. Unstimulated cells and stimulated cells served as naïve and positive controls. Figure is representative of three experiments. Significance of PEO treatment with respect to positive control is discussed in results section.