Table 1

Cytotoxicity of compounds 1 and 2 against U937 leukemia cells in vitro^a

Compd.

IC₅₀ (nM)^b

1

0.09

2

0.9

^aCells were incubated with drugs for 48 h and the experiments were performed according to our previously published method;^27bIC₅₀ values are defined as the minimal drug concentration necessary to inhibit incorporation of [³H]thymidine by 50%, and are the averages of three experiments.

Wang et al. BMC Chemical Biology 2001 1:4   doi:10.1186/1472-6769-1-4