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Open Access Highly Accessed Methodology article

RNA degradation compromises the reliability of microRNA expression profiling

David Ibberson1, Vladimir Benes1, Martina U Muckenthaler23 and Mirco Castoldi23*

Author Affiliations

1 Genomics Core Facility, EMBL, Meyerhofstraße 1 D-69117 Heidelberg, Germany

2 Department of Pediatric Oncology, Hematology and Immunology, University of Heidelberg, Im Neuenheimer Feld 156, D-69120, Heidelberg, Germany

3 Molecular Medicine Partnership Unit, Im Neuenheimer Feld 156, D-69120, Heidelberg, Germany

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BMC Biotechnology 2009, 9:102  doi:10.1186/1472-6750-9-102

Published: 21 December 2009

Additional files

Additional file 1:

Table S1 - Detailed list of degradation-regulated probes as detected by microarray. The Table contains the list of individual probes identified as regulated (i.e. for displaying fold changes of ± 2) in the microarray experiments. Data sets were correlated as indicate in the legend of Figure 6.

Format: XLS Size: 318KB Download file

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