Table 1

Characterization of HCMV Donor Sera
Donor
 BEIA-CMVa
 gBb
 CMV neutralization titerc
CMV5
 +
 +
 1:42
CMV6
 +
 -
 1:12
CMV7
 +
 +
 1:105
CMV8
 +
 -
 1:20
CMV9
 -
 -
 1:15

a. BEIA CMV ELISA detects human IgG that bind to total protein lysates from HCMV virions.

b. gB ELISA detects human IgG that bind to the AD-2 region of the HCMV envelope glycoprotein gB.

c. Sera were tested in the HCMV microneutralization assay using the AD169 strain and HELF [48]. Numbers indicate dilution of serum required for 50% inhibition of HCMV infectivity.

Funaro et al. BMC Biotechnology 2008 8:85   doi:10.1186/1472-6750-8-85