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Immunolocalization of major ECM components in control and TGF-β-treated meniscal cells
in 3D culture.
The top row presents images from control cells; the second row presents images for
(CS): A: control cells show modest CS content in the ECM. B: ECM formed by TGF-β-treated
cells shows more abundant CS compared to controls.
(Col type I) is abundant in both ECM formed by control (C) and TGF-β-treated cells
(Col type II): Control cells produced less type II collagen (E) when compared to
ECM from TGF-β-treated cells (F). Figure 5G presents a representative negative control
specimen. (For all images, bar in G = 50 μm).
Gruber et al. BMC Biotechnology 2008 8:54 doi:10.1186/1472-6750-8-54
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