|
Reduction of random integration by S-phase synchronization |
|||
| Targeting Vector |
S-phase synchronization |
# of cells |
G418rcolonies |
|
|
|||
| pHPRT+/- |
No |
107 cells |
564 |
| pHPRT+/- |
Yes |
107 cells |
20 |
|
The targeting vector used in this experiment did not contain the SV40 enhancer. | |||
Meehan et al. BMC Biotechnology 2008 8:31 doi:10.1186/1472-6750-8-31 |
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