Figure 1.

Deduced amino-acid sequences of calreticulin (Ap-CRT-1) and cathepsin-L (Ap-cath-L) from Acyrthosiphon pisum. A. Deduced protein sequence of AP-CRT-1. Secretion signal peptide of 20 AA predicted by PSORTII [20] is bold, endoplasmic reticulum retention peptide "HDEL" is italicised, signature motifs of the calreticulin family are in black boxes, conserved repeated calreticulin sequences are in grey boxes. The location of the gene sequence used to synthesize dsRNA ds1-Ap-crt-1 is underlined. B. Deduced sequence of AP-CATH-L. Secretion signal peptide of 15AA is bold, conserved residues of active site are in black boxes and conserved carboxylic side chains important for acid autocatalytic processing of L cathepsins are in grey boxes. The location of the gene sequence used to synthesize dsRNA ds1-Ap-cath-L and ds2-Ap-cath-L are underlined in black and grey, respectively.

Jaubert-Possamai et al. BMC Biotechnology 2007 7:63   doi:10.1186/1472-6750-7-63
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