Table 1

Comparison of the advantages of various apoptotic detection methods.

ASSAY

ONE-STEP

QUANTIFICATION OF LIVE, NECROTIC AND APOPTOTIC CELLS

SPECIFICITY

96-WELL FORMAT


Our 96-well-based EB/AO

+

+

+

+

Caspase 3/7 Activity

+

-

+

+

Conventional EB/AO

-

+

+

-

Annexin V/PI

-

+

+

-

ssDNA

-

-

+

+

DNA Laddering

-

-

+

-

TUNEL

-

-

-

+

DAPI stain

-

-

+

-


Ribble et al. BMC Biotechnology 2005 5:12   doi:10.1186/1472-6750-5-12

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