TaqMan fluorescence data plotted to compare the performance of MDA product with gDNA. This is a typical example of the clustering and scoring of TaqMan data for a common SNP in the evaluation of MDA product as a template for TaqMan genotyping. (a) End-point data from the 88 gDNA samples used in this evaluation and (b) the corresponding 88 MDA samples. In this example there are eight apparent failures for MDA, which are, in fact, empty wells. No genotypes were rejected for gDNA, and two genotypes were rejected for the MDA products due to poor clustering.
Pask et al. BMC Biotechnology 2004 4:15 doi:10.1186/1472-6750-4-15