Figure 2.

Cross-validation of 454 sequencing and conventional pyrosequencing: mean methylation level. Comparison of mean methylation levels for all genes in all samples: pyrosequencing and 454 sequencing data show an excellent congruence. The sequencing result of one sample (marked by an asterisk) did not pass the quality control (see Materials and Methods) and was not included in the figure. Grey columns: 454 sequencing, black columns: pyrosequencing