Table 3

Tumor Rapamycin Levels

24 hours

48 hours


Treatment Groups

Rapamycin Level (ng/ml)

p value*

Number of Mice

Rapamycin Level (ng/ml)

p value**

Number of Mice


Treatment Trial (Tumor bearing)

0.4% Direct Topical Rapamycin

13.8 ± 0.7

0.12

3

14.2 ± 1.8

0.33

3

0.8% Indirect Topical Rapamycin

34.2 ± 9.6

0.37

3

25.8 ± 7.8

0.65

3

0.8% Direct Topical Rapamycin

59.6 ± 23.5

N/A

3

21.0 ± 5.9

N/A

3

0.16 mg Rapamycin IP

421.8 ± 119.4

0.03

2

323.7 ± 98.1

0.03

2


* Compared to 0.8% direct treatment 24 hr tumor level.

** Compared to 0.8% direct treatment 48 hr tumor leve

Rauktys et al. BMC Dermatology 2008 8:1   doi:10.1186/1471-5945-8-1

Open Data