Figure 2.

Immunohistochemistry of papular lesions from three representative patients. (A) Patient 5, (B) Patient 8, (C) Patient 10. Staining with H&E, keratin 16 (K16), CD3⁺ T cells, α chain of β2 integrins CD11a (blocked by efalizumab), CD11b, CD11c, iNOS, and neutrophil elastase. There are abundant CD11b, CD11c⁺, and iNOS⁺ cells in the lesions, with relatively less CD3⁺ lymphocytes.