Two-dimensional imaging with optical coherence tomography in vivo (SkinDex 300, ISIS optronics GmbH, Mannheim, Germany) of the same sites as shown in Figure 2. The border between the cornified and living epidermis is clearly seen . Hence the extent of the stratum corneum from skin surface (SS) to the border of the viable layer (VL) could easily be assessed. A significantly thicker stratum corneum has been observed on the right ring finger (B) as compared to the left ring finger (A) [mean values of 3 assessments on different sites: 274 μm (A) vs 513 μm (B)].
Gambichler et al. BMC Dermatology 2004 4:3 doi:10.1186/1471-5945-4-3