Open Access Research article

Establishment of a murine epidermal cell line suitable for in vitro and in vivo skin modelling

Carmen Segrelles1, Almudena Holguín2, Pilar Hernández1, José M Ariza1, Jesús M Paramio1* and Corina Lorz1*

Author Affiliations

1 Molecular Oncology Unit, Epithelial Biomedicine Division, Basic Research Department, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Avd. Complutense 22, Madrid 28040, Spain

2 Regenerative Medicine Unit, Epithelial Biomedicine Division, Basic Research Department, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Avd. Complutense 22, Madrid 28040, Spain

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BMC Dermatology 2011, 11:9  doi:10.1186/1471-5945-11-9

Published: 21 April 2011

Additional files

Additional file 1:

SKY figures of representative metaphases from COCA samples at the indicated passage numbers (P). Cells display a stable translocation between chromosomes 2 and 4 (T(2;4)), and are nearly tetraploid at P77.

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