Open Access Highly Accessed Research article

Donor site morbidity in oral mucosa graft urethroplasty: implications of tobacco consumption

Rahul Janak Sinha1*, Vishwajeet Singh2, SN Sankhwar2 and Divakar Dalela2

Author Affiliations

1 Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, India

2 Department of Urology, CSMMU (formerly KGMU), Lucknow, (U.P.), India

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BMC Urology 2009, 9:15  doi:10.1186/1471-2490-9-15

Published: 21 September 2009



The purpose of this prospective study was to evaluate the donor site morbidity in patients who have undergone oral mucosa graft urethroplasty for stricture of the urethra. The impact of smoking and oral consumption of tobacco and/or paan masala on the donor site was also assessed. This study is probably the first of its kind where the affect of smoking, paan masala and tobacco chewing on the donor site morbidity has been documented.


Forty-eight patients suffering from stricture of the urethra underwent oral mucosa graft urethroplasty between July 2005 and December 2007. The patients were divided into two groups (users or non-users) based on tobacco consumption and oral hygiene. The donor site was evaluated at frequent intervals for pain, swelling, numbness, bleeding, salivation and tightness of mouth.


Donor site morbidity was more in users with poor oral hygiene. Pain scores were higher amongst the users and the morbidity persisted longer in the users compared to non-users with good oral hygiene.


Patients who consume tobacco and have poor oral hygiene should be warned regarding poorer outcomes after oral mucosa graft urethroplasty.