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Open Access Highly Accessed Case report

Langerhans cell histiocytosis on the penis: a case report

Jun Hagiuda1, Munehisa Ueno1, Satoshi Ashimine1, Isao Kuroda1*, Keisuke Ishizawa2 and Nobuhiro Deguchi1

Author Affiliations

1 Department of Urology, Saitama Medical University, Saitama, Japan

2 Department of Pathology, Saitama Medical University, Saitama, Japan

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BMC Urology 2006, 6:28  doi:10.1186/1471-2490-6-28

Published: 11 October 2006

Abstract

Background

Langerhans cell histiocytosis affects mainly young children and features an accumulation of CD1a+ dendritic Langerhans cells in the bone, skin, and other organs. A few cases of Langerhans cell histiocytosis on the penis have been reported in the literature. We present a case of Langerhans cell histiocytosis on the penis and review the similar cases in the literature.

Case presentation

The patient was a 13-year-old boy who had a history of lymph node, femur bone, and pituitary-thalmic axis lesions from Langerhans cell histiocytosis who noticed a painful nodule on the prepuce of his penis. The histological and immunohistochemical examination fulfilled the criteria of Langerhans cell histiocytosis.

Conclusion

We herein describe the case reported of Langerhans cell histiocytosis on the penis.