|
Percentage of men in all trials for whom an outcome is reported |
|||
| Outcome |
Slidenafil n = 7077 |
Tadalafil n = 2036 |
Vardenafil n = 3274 |
|
|
|||
| Efficacy |
|||
| Improved erections |
83 |
83 |
100 |
| Mean # erections/week |
20 |
0 |
0 |
| Successful attempts at SI |
47 |
72 |
100 |
| More than 60/75% successful |
10 |
0 |
18 |
| More than 40% successful |
0 |
0 |
0 |
| Final score IIEF Q3 |
94 |
27 |
26 |
| Mean change IIEF Q3 |
91 |
27 |
26 |
| Final score IIEF Q4 |
94 |
27 |
26 |
| Mean change IIEF Q4 |
91 |
27 |
26 |
| Final score EF Domain |
56 |
72 |
100 |
| Mean change EF Domain |
54 |
83 |
77 |
| Normal EF at endpoint |
8 |
56 |
14 |
| Withdrawals |
|||
| All-cause |
83 |
65 |
69 |
| Lack of efficacy |
81 |
72 |
82 |
| Adverse event |
90 |
83 |
100 |
| Adverse events |
|||
| Men with any adverse event |
42 |
40 |
18 |
| Severe |
27 |
25 |
35 |
| Serious |
38 |
83 |
78 |
| Treatment related |
55 |
3 |
43 |
| Headache |
99 |
90 |
86 |
| Dyspepsia |
79 |
71 |
73 |
| Flushing |
99 |
73 |
73 |
| Nasal congestion/rhinitis |
64 |
35 |
73 |
| Visual disturbances |
89 |
46 |
55 |
| Back pain |
13 |
73 |
9 |
| Myalgia/increased CPK |
16 |
60 |
18 |
| Flu syndrome |
17 |
30 |
34 |
| CV events |
24 |
27 |
33 |
| Limb pain |
10 |
11 |
0 |
| Fatigue |
3 |
15 |
0 |
| Priapism |
29 |
0 |
0 |
| Nausea |
14 |
0 |
0 |
Moore et al. BMC Urology 2005 5:18 doi:10.1186/1471-2490-5-18 |
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