Table 3

Organ-specific stromal mesenchyme cell genes. Listed are the candidates identified through array analysis. Fold difference in the last column of each grouping provides a rough estimate of the level of differential expression between the two cell types.

Prostate Stromal Genes

Bladder Stromal Genes


Gene Description

Gene

Fold

Gene Description

Gene

Fold


proenkephalin

PENK

26.41

B-factor, properdin

BF

44.23

stanniocalcin 1

STC1

20.86

argininosuccinate synthetase

ASS

19.36

trophinin

TRO

13.41

methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase

MTHFD2

19.04

RAB27B, member RAS oncogene family

RAB27B

12.27

claudin 11 (oligodendrocyte transmembrane protein)

CLDN11

18.25

REV3-like, catalytic subunit of DNA polymerase z (yeast)

REV3L

10.68

interleukin 1, b

IL1B

17.57

CD59 antigen p18-20

CD59

10.19

carbonic anhydrase XII

CA12

16.49

matrix metalloproteinase 3 (stromelysin 1, progelatinase)

MMP3

10.06

pirin

PIR

15.52

homolog of rat orphan transporter v7-3

NTT73

9.12

osteoblast specific factor 2 (fasciclin I-like)

OSF-2

14.59

ras-induced senescence 1

RIS1

9.05

asparagine synthetase

ASNS

12.96

chondroitin b1,4 N-acetylgalactosaminyltransferase

ChGn

6.9

inositol(myo)-1(or 4)-monophosphatase 2

IMPA2

9.85

bone morphogenetic protein 2

BMP2

6.68

aldehyde dehydrogenase 1 family, member A1

ALDH1A1

9.48

sprouty homolog 4 (Drosophila)

SPRY4

6.29

prostaglandin I2 (prostacyclin) synthase

PTGIS

9.24

endothelin receptor type B

EDNRB

5.46

aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-a (3-a)-hydroxysteroid dehydrogenase)

AKR1C1

9.2

interleukin 7 receptor

IL7R

5.44

BCL2 binding component 3

BBC3

9.06

tenascin C (hexabrachion)

TNC

5.29

chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)

CXCL12

8.65

tissue factor pathway inhibitor 2

TFPI2

5.13

activin A receptor, type II

ACVR2

8.03

plasminogen activator

PLAT

5.09

hyaluronan synthase 3

HAS3

7.34

transcription factor 21

TCF21

4.76

GDNF family receptor a1

GFRA1

7.12

KIAA1373 protein

KIAA1373

4.42

activating transcription factor 5

ATF5

6.31

UDP-N-acetyl-a-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7

GALNT7

4.25

protein tyrosine phosphatase, receptor type, D

PTPRD

5.76

SEC14-like 2 protein (S. cerevisiae)

SEC14L2

3.54

growth arrest-specific 1

GAS1

5.49

gap junction protein, a7, 45kDa (connexin 45)

GJA7

3.21

Ca2+-dependent activator protein for secretion

CADPS

5.25

paired-like homeodomain transcription factor 2

PITX2

4.86

tryptophanyl-tRNA synthetase

WARS

4.76

phosphogluconate dehydrogenase

PGD

4.56

CUG triplet repeat, RNA binding protein 2

CUGBP2

4.46

GATA binding protein 6

GATA6

4.4

collectin sub-family member 12

COLEC12

3.94

stanniocalcin 2

STC2

3.86


Goo et al. BMC Urology 2005 5:17   doi:10.1186/1471-2490-5-17

Open Data