Table 3

Global H4K20 methylation levels are correlated to adverse clinical-pathological parameters

H4K20me1

H4K20me2

H4K20me3


preoperative PSA†

p = 0.122

p = 0.573

p = 0.151

pT-stage

p = 0.122

p = 0.573

p = 0.157

capsular penetration

p = 0.094

p = 0.469

p = 0.902

seminal vesicle infiltration

p = 0.127

p = 0.947

p = 0.468

lymph node metastases

p = 0.002

p = 0.196

p = 0.091

Gleason Score‡

p = 0.191

p = 0.021

p = 0.074


† categorized: PSA < 4 ng/ml, 4-10 ng/ml, > 10 ng/ml; ‡ categorized: Gleason Sum ≤ 6, 7, ≥ 8

Behbahani et al. BMC Urology 2012 12:5   doi:10.1186/1471-2490-12-5

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